Collegium Pharmaceutical, Inc (COLL)

Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. The company's portfolio includes Jornay PM, a central nervous system stimulant prescription medicine that contains methylphenidate HCl for the treatment of attention deficit hyperactivity disorder; Belbuca, a buccal film that contains buprenorphine for severe and persistent pain that requires an extended treatment period; Xtampza ER, an abuse-deterrent, extended-release, oral formulation of oxycodone for the management of pain severe enough to require daily; Nucynta ER and Nucynta IR, which are extended-release and immediate-release oral formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; and Symproic, an oral formulation of naldemedine for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain. Collegium Pharmaceutical, Inc. was formerly known as Collegium Pharmaceuticals, Inc. and changed its name to Collegium Pharmaceutical, Inc. in October 2003. The company was incorporated in 2002 and is headquartered in Stoughton, Massachusetts.

Ticker
COLL
Exchange
Nasdaq
Sector
Healthcare
Industry
Drug Manufacturers - Specialty & Generic
Market cap
$752.25M
52-week range
$21.43 - $50.79

Valuation

Share price
$24.21 (close of Nov 6, 2026)
P/E (TTM)
19.84x
Price to book
2.54x
Price to free cash flow
2.24x
Enterprise value
$1.69B
Book value per share
$9.54

Price performance

PeriodChange
1 day-3.78%
5 days+1.72%
1 month+10.65%
3 months-16.83%
6 months-33.69%
Year to date-47.71%
1 year-40.46%
3 years+9.55%
5 years+27.02%
10 years+69.06%
All time+96.99%

Short interest

As of
Oct 15, 2026
Short % of float
19.72%
Shares short
5.38M
Days to cover
7.17
Change since prior report
-2.57%
Source
FINRA consolidated short interest

Profitability and growth

Return on equity
20.84%
Return on invested capital
13.42%
Return on assets
3.79%
Return on capital employed
14.76%
Gross margin
59.35%
Net margin
8.05%
EBITDA margin
51.98%
Revenue growth
23.62%
Net income growth
-9.13%
Free cash flow growth
61.11%

Cash flow and balance sheet

Free cash flow yield (TTM)
44.70%
Current ratio
1.01x
Net debt to EBITDA
2.68x

Latest reported year

Period end
Dec 31, 2025
Fiscal year
2025
Revenue
$780.57M
Cost of revenue
$317.31M
Gross profit
$463.26M
EBITDA
$405.71M
Net income
$62.87M
Earnings per share
$1.98
Interest expense
$82.31M
Shares outstanding
31.71M

Income statement by year

Period endRevenueGross profitNet incomeEPS
2025-12-31$780.57M$463.26M$62.87M$1.98
2024-12-31$631.45M$377.34M$69.19M$2.14
2023-12-31$566.77M$326.17M$48.16M$1.43
2022-12-31$463.93M$209.49M-$25.00M-$0.74
2021-12-31$276.87M$150.62M$71.52M$2.05
2020-12-31$310.02M$179.84M$26.75M$0.78
2019-12-31$296.70M$103.04M-$22.72M-$0.68
2018-12-31$280.41M$114.74M-$39.13M-$1.19
2017-12-31$28.48M$25.88M-$74.86M-$2.47
2016-12-31$1.71M$1.50M-$94.18M-$3.88

Margins and returns by year

Period endGross marginNet marginReturn on equityReturn on capital
2025-12-3159.35%8.05%20.84%13.42%
2024-12-3159.76%10.96%30.23%12.91%
2023-12-3157.55%8.50%24.64%16.03%
2022-12-3145.15%-5.39%-12.83%3.69%
2021-12-3154.40%25.83%35.24%5.01%
2020-12-3158.01%8.63%14.38%18.77%
2019-12-3134.73%-7.66%-25.99%-21.78%
2018-12-3140.92%-13.95%-42.72%-20.07%
2017-12-3190.89%-262.91%-71.93%-72.49%
2016-12-3187.55%-5,504.15%-69.81%-67.66%

Cash and debt by year

Period endCashDebt
2025-12-31$231.25M$238.21M
2024-12-31$70.56M$237.17M
2023-12-31$238.95M$262.13M
2022-12-31$173.69M$140.87M
2021-12-31$186.43M$139.97M
2020-12-31$174.12M$99.58M
2019-12-31$170.02M$11.50M
2018-12-31$146.63M$11.50M
2017-12-31$118.70M-
2016-12-31$153.22M$4.15M

Free cash flow by year

Period endFree cash flowStock-based compensation
2025-12-31$327.58M$41.91M
2024-12-31$203.33M$32.40M
2023-12-31$274.29M$27.14M
2022-12-31$122.61M$22.87M
2021-12-31$101.61M$24.25M
2020-12-31$88.40M$21.91M
2019-12-31$21.34M$16.53M
2018-12-31$163.91M$13.78M
2017-12-31-$68.01M$7.95M
2016-12-31-$75.53M$5.79M

Investor relations

Past earnings dates

ReportedFiscal periodEPS estimate
2026-11-05Sep 2026$1.53
2026-08-06Jun 2026$1.48
2026-05-07Mar 2026$1.23
2026-02-26Dec 2025$2.01
2025-11-06Sep 2025$1.69
2025-08-07Jun 2025$1.43
2025-05-08Mar 2025$1.29
2025-02-27Dec 2024$1.41

Filings and sources

Company website
collegiumpharma.com
SEC filings
10-K, 10-Q and 8-K on EDGAR
Earnings calendar
All upcoming reports

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