Revolution Medicines, Inc. (RVMD)

Revolution Medicines, Inc., a clinical-stage precision oncology company, develops novel targeted therapies for RAS-addicted cancers. The company's research and development pipeline consist of RAS(ON) inhibitors that binds RAS variants to be used as monotherapy in combination with other RAS(ON) inhibitors and/or in combination with RAS companion inhibitors or other therapeutic agents, and RAS companion inhibitors to suppress cooperating targets and pathways that sustain RAS-addicted cancers. Its RAS(ON) inhibitors include daraxonrasib (RMC-6236), elironrasib G12C (RMC-6291) which is in early clinical development for the treatment of solid tumors, and zoldonrasib G12D (RMC-9805), which are in phase 3 registrational trial evaluating the combination of daraxonrasib with zoldonrasib in patients with 1L PDAC; and development candidates comprise RMC-5127 (G12V) which is in clinical trial, RMC-0708 (Q61H), that is in clinical trial; and RMC-8839 (G13C). Revolution Medicines, Inc. was incorporated in 2014 and is headquartered in Redwood City, California.

Symbol
RVMD
Exchange
Nasdaq
Sector
Healthcare
Industry
Biotechnology
Market cap
$41.32B
52 week range
42.18 - 224.31

Valuation

Share price
$190.74 (close of 2026-09-23)
P/E (TTM)
-21.77x
Price to book
15.85x
Price to free cash flow
-33.53x
Enterprise value
$41.15B
Book value per share
$12.16

Price performance

PeriodChange
1 day-1.05%
5 days-6.89%
1 month-8.94%
3 months+12.52%
6 months+97.39%
Year to date+139.47%
1 year+331.44%
3 years+535.80%
5 years+497.56%
All time+560.00%

Profitability and growth

Return on equity
-69.35%
Return on invested capital
-84.08%
Return on assets
-48.05%
Return on capital employed
-57.28%
Revenue growth
0.00%
Net income growth
-88.52%
Free cash flow growth
-60.94%

Cash flow and balance sheet

Free cash flow yield (TTM)
-2.98%
Current ratio
11.38x
Net debt to EBITDA
0.10x

Latest reported year

Period end
2025-12-31
Fiscal year
2025
EBITDA
$-1.17B
Net income
$-1.13B
Earnings per share
$-5.95
Research and development
$987.33M
Shares outstanding
190.13M

Income statement by year

Period endRevenueNet incomeEPS
2025-12-31-$-1.13B$-5.95
2024-12-31-$-600.09M$-3.58
2023-12-31$11.58M$-436.37M$-3.86
2022-12-31$35.38M$-248.71M$-3.08
2021-12-31$29.39M$-187.09M$-2.57
2020-12-31$42.98M$-108.16M$-2.01
2019-12-31$50.04M$-47.66M$-22.33
2018-12-31$20.16M$-41.79M$-21.24

Margins and returns by year

Period endNet marginReturn on equityReturn on capital
2025-12-31--69.35%-84.08%
2024-12-31--26.49%-37.07%
2023-12-31-3768.28%-23.89%-39.71%
2022-12-31-702.95%-36.30%-43.85%
2021-12-31-636.58%-31.05%-33.53%
2020-12-31-251.63%-22.79%-27.37%
2019-12-31-95.25%31.24%-
2018-12-31-207.24%38.54%-

Cash and debt by year

Period endCash
2025-12-31$383.75M
2024-12-31$543.06M
2023-12-31$696.15M
2022-12-31$161.41M
2021-12-31$108.50M
2020-12-31$104.27M
2019-12-31$16.66M

Free cash flow by year

Period endFree cash flowStock-based compensation
2025-12-31$-913.73M$118.39M
2024-12-31$-567.74M$79.20M
2023-12-31$-358.30M$61.77M
2022-12-31$-235.22M$31.20M
2021-12-31$-153.71M$20.72M
2020-12-31$-103.00M$8.89M
2019-12-31$-52.20M$3.16M
2018-12-31$-286.00K$855.00K

Investor relations

Next earnings report

Next confirmed report
2026-11-04

Past earnings dates

ReportedFiscal periodEPS estimate
2026-08-05Jun/2026-
2026-05-06--
2026-02-25--
2025-11-05--
2025-08-06--
2025-05-07--
2025-02-26--
2024-11-06--

Filings and sources

Company website
revmed.com
SEC filings
10-K, 10-Q and 8-K on EDGAR
Earnings calendar
All upcoming reports

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