Tempus AI, Inc. (TEM)

Tempus AI, Inc. operates as a healthcare technology company in the United States. It offers the Tempus platform, a closed-loop, full-stack, bi-directional integrations between a clinician's desktop and its laboratory diagnostic capabilities, analytics platform, and repository of multimodal data; and Hub, a clinical application for physicians and other healthcare providers for use in the diagnostics product line as an end-to-end application for healthcare providers for NGS tests. The company also provides Lens, a software application for life sciences and advanced precision research; diagnostics services, such as NGS diagnostics, PCR profiling, and other anatomic and molecular pathology tests; and large-panel solid tumor and hematologic testing through multiple assays, with its core clinical assay (xT and xR) offering large panel DNA, RNA full transcriptome, and incidental germline findings through normal blood or saliva analyses. In addition, it provides genetic tests focused on inherited conditions; an nP assay for pharmacogenomic testing for patients with psychiatric conditions, including depression, general anxiety disorder, bipolar disorder, and other relevant diagnoses; Insights, which licenses libraries of linked, de-identified clinical, molecular, and imaging data; Organoids, a tumor derived biological modeling. Further, the company offers Trials for clinical trial matching services; Next, an AI platform; Algos, an algorithm-based diagnostics application. It has Strategic Collaborations with AstraZeneca AB, Pathos AI, Inc., GlaxoSmithKline, Merck, and Recursion Pharmaceuticals, Inc. Additionally, it also has a strategic collaboration with Blood Cancer United to develop registry for pediatric acute myeloid leukemia. The company was formerly known as Tempus Labs, Inc. and changed its name to Tempus AI, Inc. in January 2023. Tempus AI, Inc. was incorporated in 2015 and is headquartered in Chicago, Illinois.

Ticker
TEM
Exchange
Nasdaq
Sector
Healthcare
Industry
Health Information Services
Market cap
$13.87B
52-week range
$40.77 - $89.09

Valuation

Share price
$76.05 (close of Nov 6, 2026)
P/E (TTM)
-72.43x
Price to book
27.72x
Price to free cash flow
-101.41x
Enterprise value
$14.71B
Book value per share
$2.74

Price performance

PeriodChange
1 day+7.98%
5 days+5.30%
1 month+5.65%
3 months+64.90%
6 months+42.15%
Year to date+28.79%
1 year+5.49%
All time+88.94%

Short interest

As of
Oct 15, 2026
Short % of float
24.95%
Shares short
25.38M
Days to cover
3.55
Change since prior report
+1.02%
Source
FINRA consolidated short interest

Profitability and growth

Return on equity
-49.87%
Return on invested capital
-11.06%
Return on assets
-10.77%
Return on capital employed
-13.29%
Gross margin
51.25%
Net margin
-19.27%
EBITDA margin
-17.36%
Revenue growth
83.41%

Cash flow and balance sheet

Free cash flow yield (TTM)
-0.99%
Current ratio
2.61x
Net debt to EBITDA
-26.61x

Latest reported year

Period end
Dec 31, 2025
Fiscal year
2025
Revenue
$1.27B
Cost of revenue
$620.00M
Gross profit
$651.79M
EBITDA
-$220.82M
Net income
-$245.03M
Earnings per share
$-1.41
Research and development
$172.92M
Shares outstanding
174.26M

Income statement by year

Period endRevenueGross profitNet incomeEPS
2025-12-31$1.27B$651.79M-$245.03M-$1.41
2024-12-31$693.40M$213.59M-$705.81M-$6.23
2023-12-31$531.82M$191.02M-$214.12M-$4.20
2022-12-31$320.67M$51.09M-$289.81M-$5.30
2021-12-31$257.85M--$259.19M-
2020-12-31$188.00M--$209.85M-
2019-12-31$62.06M--$114.95M-

Margins and returns by year

Period endGross marginNet marginReturn on equityReturn on capital
2025-12-3151.25%-19.27%-49.87%-11.06%
2024-12-3130.80%-101.79%--131.78%
2023-12-3135.92%-40.26%--
2022-12-3115.93%-90.38%--
2021-12-31--100.52%--
2020-12-31--111.62%--
2019-12-31--185.23%--

Cash and debt by year

Period endCashDebt
2025-12-31$604.79M$308.67M
2024-12-31$340.95M$168.19M
2023-12-31$165.77M$193.12M
2022-12-31$302.94M-
2021-12-31$277.69M-
2020-12-31$513.44M-
2019-12-31$227.60M-

Free cash flow by year

Period endFree cash flowStock-based compensation
2025-12-31-$239.14M$124.75M
2024-12-31-$211.17M$534.14M
2023-12-31-$248.95M-
2022-12-31-$186.58M-
2021-12-31-$223.75M$559.00K
2020-12-31-$219.98M$399.00K
2019-12-31-$134.15M$529.00K

Investor relations

Past earnings dates

ReportedFiscal periodEPS estimate
2026-11-02Sep 2026-$0.32
2026-07-30Jun 2026-$0.41
2026-05-05Mar 2026-$0.47
2026-02-24Dec 2025-$0.27
2025-11-04Sep 2025-$0.37
2025-08-08Jun 2025-$0.47
2025-05-06Mar 2025-$0.47
2025-02-24Dec 2024-$0.31

Filings and sources

Company website
tempus.com
SEC filings
10-K, 10-Q and 8-K on EDGAR
Earnings calendar
All upcoming reports

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