Adaptive Biotechnologies Corp (ADPT)

Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases. The company offers immunosequencing platform which combines a suite of proprietary chemistry, computational biology, and machine learning to generate clinical immunomics data to decode the adaptive immune system. It provides clonoSEQ diagnostic test which detects and monitors the remaining number of cancer cells that are present in a patient's body during and after treatment, known as Minimal Residual Disease (MRD). The company offers products and services for life sciences research, clinical diagnostics, and drug discovery applications. The company was formerly known as Adaptive TCR Corporation and changed its name to Adaptive Biotechnologies Corporation in December 2011. Adaptive Biotechnologies Corporation was incorporated in 2009 and is headquartered in Seattle, Washington.

Symbol
ADPT
Exchange
Nasdaq
Sector
Healthcare
Industry
Diagnostics & Research
Market cap
$4.44B
52 week range
12 - 28.78

Valuation

Share price
$27.89 (close of 2026-09-23)
P/E (TTM)
-69.72x
Price to book
29.44x
Price to free cash flow
-184.58x
Enterprise value
$4.68B
Book value per share
$0.95

Price performance

PeriodChange
1 day+0.11%
5 days+4.54%
1 month+7.31%
3 months+61.87%
6 months+104.17%
Year to date+71.74%
1 year+100.22%
3 years+450.10%
5 years-28.89%
All time-30.80%

Profitability and growth

Return on equity
-26.44%
Return on invested capital
-24.45%
Return on assets
-11.60%
Return on capital employed
-13.51%
Gross margin
74.24%
Net margin
-21.48%
EBITDA margin
-14.80%
Revenue growth
54.77%
Net income growth
62.69%
Free cash flow growth
50.50%

Cash flow and balance sheet

Free cash flow yield (TTM)
-0.54%
Current ratio
4.79x
Net debt to EBITDA
-6.62x

Latest reported year

Period end
2025-12-31
Fiscal year
2025
Revenue
$276.98M
Cost of revenue
$71.36M
Gross profit
$205.62M
EBITDA
$-40.99M
Net income
$-59.50M
Earnings per share
$-0.39
Research and development
$93.77M
Interest expense
$11.78M
Shares outstanding
151.72M

Income statement by year

Period endRevenueGross profitNet incomeEPS
2025-12-31$276.98M$205.62M$-59.50M$-0.39
2024-12-31$178.96M$106.88M$-159.49M$-1.08
2023-12-31$170.28M$94.72M$-225.25M$-1.56
2022-12-31$185.31M$127.40M$-200.19M$-1.40
2021-12-31$154.34M$105.04M$-207.28M$-1.48
2020-12-31$98.38M$75.85M$-146.23M$-1.11
2019-12-31$85.07M$62.80M$-68.61M$-1.01
2018-12-31$55.66M$35.99M$-46.45M$-3.67
2017-12-31$38.45M$22.77M$-42.83M$-3.50

Margins and returns by year

Period endGross marginNet marginReturn on equityReturn on capital
2025-12-3174.24%-21.48%-26.44%-24.45%
2024-12-3159.72%-89.12%-78.77%-66.63%
2023-12-3155.63%-132.29%-73.07%-66.39%
2022-12-3168.75%-108.03%-43.14%-41.53%
2021-12-3168.06%-134.30%-34.31%-36.23%
2020-12-3177.10%-148.63%-19.67%-21.00%
2019-12-3173.82%-80.65%-12.01%-15.34%
2018-12-3164.67%-83.44%17.99%-
2017-12-3159.22%-111.40%19.07%-

Cash and debt by year

Period endCashDebt
2025-12-31$70.50M$126.57M
2024-12-31$47.92M$132.41M
2023-12-31$65.06M$130.66M
2022-12-31$90.03M$125.36M
2021-12-31$139.06M-
2020-12-31$123.44M-
2019-12-31$96.58M-
2018-12-31$55.03M-

Free cash flow by year

Period endFree cash flowStock-based compensation
2025-12-31$-48.95M$51.48M
2024-12-31$-98.88M$53.61M
2023-12-31$-167.02M$62.91M
2022-12-31$-200.29M$55.48M
2021-12-31$-254.47M$43.25M
2020-12-31$-168.49M$24.76M
2019-12-31$194.20M$13.12M
2018-12-31$-38.56M$11.15M
2017-12-31$-37.28M$7.01M

Investor relations

Next earnings report

Next confirmed report
2026-11-04

Past earnings dates

ReportedFiscal periodEPS estimate
2026-07-29Jun/2026-
2026-05-05--
2026-02-05--
2025-11-05--
2025-08-05--
2025-05-01--
2025-02-12--
2025-02-11--

Filings and sources

Company website
adaptivebiotech.com
SEC filings
10-K, 10-Q and 8-K on EDGAR
Earnings calendar
All upcoming reports

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Price-to-earnings ratio · Discounted cash flow · Free cash flow · Earnings per share · Return on equity · Gross margin vs net margin · Reading a balance sheet · Debt and leverage · Dividend yield · Insider transactions and Form 4 · How to read a stock chart

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