Illumina, Inc. (ILMN)

Illumina, Inc. provides sequencing- and array-based solutions for genetic and genomic analysis in the Americas, Europe, Greater China, the Asia Pacific, the Middle East, and Africa. The company offers sequencing- and array-based instruments and consumables, which include reagents, flow cells, and library preparation; whole-genome sequencing kits, which sequence entire genomes of various size and complexity; and targeted resequencing kits, which sequence exomes, specific genes, and RNA or other genomic regions of interest. It also provides whole-genome sequencing, genotyping, noninvasive prenatal testing, and product support services. The company serves genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies. The company markets and distributes its products directly to customers, as well as through life-science distributors. The company has a collaboration with Labcorp Holdings Inc. for the development of oncology treatments through applications of sequencing solutions across the healthcare ecosystem; and strategic collaboration with Integrated DNA Technologies to enable a DRAGEN, secondary analysis pipeline for IDT xGena, FFPE and cfDNA next generation sequencing (NGS) library preparation with custom panels, delivering an integrated, end-to-end solution for somatic oncology research. It also has a data partnership with Center for Data-Driven Discovery in Biomedicine to advance research in pediatric cancer and rare disease. Illumina, Inc. was incorporated in 1998 and is headquartered in San Diego, California.

Ticker
ILMN
Exchange
Nasdaq
Sector
Healthcare
Industry
Diagnostics & Research
Market cap
$32.18B
52-week range
$112.65 - $309.35

Valuation

Share price
$213.13 (close of Nov 6, 2026)
P/E (TTM)
36.25x
Price to book
10.23x
Price to free cash flow
30.45x
Enterprise value
$33.16B
Book value per share
$20.83

Price performance

PeriodChange
1 day+2.47%
5 days-9.69%
1 month-22.08%
3 months+10.02%
6 months+49.48%
Year to date+62.50%
1 year+75.98%
3 years+94.16%
5 years-46.32%
10 years+62.74%
All time+1,018.65%

Short interest

As of
Oct 15, 2026
Short % of float
8.45%
Shares short
7.89M
Days to cover
2.94
Change since prior report
-16.75%
Source
FINRA consolidated short interest

Members of Congress who disclosed ILMN trades

Lisa McClain · Thomas Kean · Gilbert Ray Cisneros

Super investors holding ILMN

Samantha McLemore (Patient Capital Management, LLC) · Ray Dalio (Bridgewater Associates)

Profitability and growth

Return on equity
31.22%
Return on invested capital
10.82%
Return on assets
12.79%
Return on capital employed
15.95%
Gross margin
66.08%
Net margin
19.57%
EBITDA margin
24.80%
Revenue growth
-0.66%
Free cash flow growth
31.31%

Cash flow and balance sheet

Free cash flow yield (TTM)
3.28%
Current ratio
2.63x
Net debt to EBITDA
0.71x

Latest reported year

Period end
Dec 28, 2025
Fiscal year
2025
Revenue
$4.34B
Cost of revenue
$1.47B
Gross profit
$2.87B
EBITDA
$1.08B
Net income
$850.00M
Earnings per share
$5.47
Research and development
$967.00M
Interest expense
$101.00M
Shares outstanding
155.00M

Income statement by year

Period endRevenueGross profitNet incomeEPS
2025-12-28$4.34B$2.87B$850.00M$5.47
2024-12-29$4.37B$2.86B-$1.22B-$7.69
2023-12-31$4.50B$2.74B-$1.16B-$7.34
2023-01-01$4.58B$2.97B-$4.40B-$28.00
2022-01-02$4.53B$3.15B$762.00M$5.07
2021-01-03$3.24B$2.20B$656.00M$4.48
2019-12-29$3.54B$2.47B$1.00B$6.81
2018-12-30$3.33B$2.30B$826.00M$5.63
2017-12-31$2.75B$1.83B$726.00M$4.96
2017-01-01$2.40B$1.67B$463.00M$3.09

Margins and returns by year

Period endGross marginNet marginReturn on equityReturn on capital
2025-12-2866.08%19.57%31.22%10.82%
2024-12-2965.44%-27.97%-51.54%-16.68%
2023-12-3160.92%-25.78%-20.21%-13.35%
2023-01-0164.83%-96.07%-66.74%-41.16%
2022-01-0269.69%16.84%7.09%-1.00%
2021-01-0368.01%20.25%13.98%5.76%
2019-12-2969.63%28.28%21.72%13.20%
2018-12-3069.01%24.78%21.48%11.28%
2017-12-3166.35%26.38%26.41%7.47%
2017-01-0169.47%19.31%20.40%13.61%

Cash and debt by year

Period endCashDebt
2025-12-28$1.63B-
2024-12-29$1.22B-
2023-12-31$1.05B-
2023-01-01$2.04B-
2022-01-02$1.34B$702.00M
2021-01-03$3.47B$673.00M
2019-12-29$3.41B$1.14B
2018-12-30$3.51B$890.00M
2017-12-31$2.15B$1.18B
2017-01-01$1.56B$1.06B

Free cash flow by year

Period endFree cash flowStock-based compensation
2025-12-28$931.00M$275.00M
2024-12-29$709.00M$370.00M
2023-12-31$283.00M$380.00M
2023-01-01$106.00M$366.00M
2022-01-02$337.00M$754.00M
2021-01-03$891.00M$194.00M
2019-12-29$842.00M$194.00M
2018-12-30$846.00M$193.00M
2017-12-31$565.00M$164.00M
2017-01-01$519.00M$129.00M

Investor relations

Past earnings dates

ReportedFiscal periodEPS estimate
2026-10-29Sep 2026$1.36
2026-07-30Jun 2026$1.23
2026-04-30Mar 2026$1.05
2026-02-05Dec 2025$1.26
2025-10-30Sep 2025$1.16
2025-07-31Jun 2025$1.02
2025-05-08Mar 2025$0.96
2025-02-06Dec 2024$0.92

Filings and sources

Company website
illumina.com
SEC filings
10-K, 10-Q and 8-K on EDGAR
Earnings calendar
All upcoming reports

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